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AN INTRODUCTION It is one of the most common hereditary bleeding disorders in which the blood is unable to clot properly. Von Willebrand Factor (VBF) is the protein factor that is required for the blood clotting process. The deficiency of this factor in the blood causes bleeding disorders for a lifetime. It cannot be cured […]

WHAT IS ANTIPHOSPHOLIPID SYNDROME? Antiphospholipid is a syndrome that generally affects younger women. It is an autoimmune disease in which the immune system of the affected person mistakenly produces antibodies that attack the tissues of the body. These antibodies in turn cause the formation of clots in the veins as well as in the arteries.

PROTHROMBIN GENE MUTATION: AN OVERVIEW Prothrombin Gene Mutation is also known as Factor II Mutation or Prothrombin G20210A. It is an inherited disease that causes the human body to produce more amounts of prothrombin. Prothrombin is a protein that is needed for the formation of a blood clot. The patient who suffers from this condition

Long-term anticoagulation therapy is for patients suffering from bleeding disorders or any the major diseases such as- °      Atrial Fibrillation °      Mechanical Cardiac Valve Replacement °      Venous Thromboembolism (Deep vein thrombosis and Pulmonary embolism) °       Thromboembolic events °      Post-Myocardial Infarction °       Systemic Embolic events The most common oral-anticoagulant prescribed to such patients is WARFARIN (COUMADIN). Patients who are on blood-thinning medications are completely under regular monitoring

LEARNING ABOUT – BLOOD CLOTS A blood clot is a mass of blood that sticks together to form at the site of injury. The platelets, proteins and cells of the body combine to form a clot that stops the bleeding from the injury site. Once the healing process begins the blood clot is automatically degenerated.

WHAT IS ACUTE LIVER FAILURE?   Acute Liver Failure is a rare medical condition that occurs when your liver loses its ability to function suddenly. It is more prominent in patients who are not suffering from any pre-existing liver disease or cirrhosis. Those patients who have an  INR of 1.5 or higher  are also at a

INTRODUCTION TO COAGULATION TESTS When any minor injury or cut happens, we bleed. In most healthy people the bleeding stops. But a person who is suffering from bleeding disorders can suffer major consequences from even a minor cut. Excessive bleeding can be quite dangerous or even fatal. Clotting is what prevents excessive or severe bleeding.

WHAT TO UNDERSTAND ABOUT CIRCULATING ANTICOAGULANTS?   The circulating anticoagulants are usually autoantibodies that do the work of neutralizing specific coagulation proteins present in the blood. This applies in particular to coagulating protein factor VIII OR V., It can usually be diagnosed in patients who are suffering from excessive bleeding and whose PTT & PT

WHAT YOU SHOULD KNOW ABOUT DISSEMINATED INTRAVASCULAR COAGULATION SYNDROME   Disseminated Intravascular Syndrome is a serious medical condition that disrupts the path of blood flow. With this condition, the proteins responsible for clotting become overactive. During this, small blood clots begin to develop in the blood vessels causing a blockage in blood flow. This leads

INTRODUCTION TO FACTOR XI DEFICIENCY   Factor XI is one of the important blood-clotting proteins that is required to complete the blood clotting factor efficiently. The deficiency of this clotting factor can cause bleeding disorders in the human body. Also known as Hemophilia C, it is one of the most important coagulating proteins that help