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CEREBRAL VENOUS THROMBOSIS IN THE PUERPERIUM: A RARE BUT DANGEROUS COMPLICATION OF PREGNANCY

Puerperium is a crucial period in a woman’s life. It is the time from the delivery of a baby to the return of the reproductive system to its pre-pregnancy state. During this period, women are susceptible to several complications, one of which is cerebral venous thrombosis (CVT). CVT is a rare but potentially life-threatening condition that occurs due to the formation of a blood clot in the veins in the brain.

In this blog, we will discuss the symptoms, causes, diagnosis, complications, risk factors, and treatment options for cerebral venous thrombosis in the puerperium.

THE UNDERLYING SYMPTOMS 

CVT can present with a variety of symptoms, which can be subtle or severe. Some common symptoms include:

  • Headache – A severe, throbbing headache that worsens over time is a hallmark symptom of CVT
  • Vision changes – Blurred vision or loss of vision in one or both eyes can occur.
  • Seizures – Seizures can occur in some cases.
  • Nausea and vomiting – Women with CVT may experience nausea and vomiting.
  • Weakness – Some women may feel weak, tired, or lethargic.
  • Confusion – Confusion, disorientation, or memory loss may occur.
  • Sensitivity to light – Women with CVT may experience sensitivity to light.
  • Difficulty speaking – Difficulty speaking or slurred speech can be a symptom of CVT.
  • Swelling in the legs – Swelling in the legs, arms, or other parts of the body may occur.

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CAUSES

CVT can occur due to several factors, including:

  • Dehydration – Dehydration can increase the risk of blood clot formation.
  • Hormonal changes – Hormonal changes during pregnancy and the puerperium can increase the risk of blood clot formation.
  • Infections – Infections, particularly those involving the head and neck, can increase the risk of CVT.
  • Trauma – Trauma to the head or neck can increase the risk of CVT.
  • Blood disorders – Blood disorders, such as thrombophilia, can increase the risk of CVT.

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DIAGNOSIS

Diagnosing CVT can be challenging, as the symptoms can be non-specific and similar to other conditions. However, some diagnostic tests can help confirm the diagnosis, including:

  • Magnetic resonance imaging (MRI) – MRI can detect blood clots in the brain’s veins.
  • Magnetic resonance venography (MRV) – MRV is a specialized MRI that can provide detailed images of the veins.
  • Computed tomography (CT) – CT can detect blood clots in the brain’s veins.
  • Cerebral angiography – Cerebral angiography is a specialized test that uses X-rays and contrast dye to visualize the brain’s blood vessels.

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COMPLICATIONS 

CVT can lead to several complications, including:

  • Brain damage – If left untreated, CVT can cause permanent brain damage.
  • Seizures – Seizures can occur in some cases.
  • Stroke – CVT can cause a stroke, which can lead to permanent disability or death.
  • Hydrocephalus – Hydrocephalus is a condition that occurs due to the buildup of cerebrospinal fluid in the brain. CVT can cause hydrocephalus.
  • Increased intracranial pressure – CVT can cause increased intracranial pressure, which can lead to severe headaches, nausea, vomiting, and other symptoms.

RISK FACTORS

Some women are more likely to develop CVT during the puerperium, including:

  • Women who have had a previous blood clot
  • Women who have a family history of blood clots
  • Women who have underlying medical conditions, such as thrombophilia, lupus, or cancer.
  • Women who have had prolonged labor or a cesarean section delivery.
  • Women who are obese or have a body mass index (BMI) of 30 or above.
  • Women who smoke.

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LINE OF TREATMENT

The treatment of CVT in the puerperium depends on the severity of the condition and the underlying cause. Some common treatment options include:

  • Anticoagulant therapy – Anticoagulant therapy involves the use of blood-thinning medications to prevent the formation of blood clots.
  • Thrombectomy – Thrombectomy is a surgical procedure that involves the removal of the blood clot.
  • Endovascular treatment – Endovascular treatment involves the use of a catheter to deliver medication directly to the site of the blood clot.
  • Supportive care – Supportive care, such as pain management, hydration, and monitoring of intracranial pressure, can help manage symptoms and prevent complications.

CONCLUSION

In conclusion, cerebral venous thrombosis is a rare but potentially life-threatening condition that can occur during the puerperium. Women who experience any symptoms of CVT should seek medical attention immediately. Early diagnosis and prompt treatment can prevent complications and improve outcomes. Preventing CVT during the puerperium involves reducing the risk factors and taking appropriate preventive measures. 

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Patients who are on blood thinning medications such as WARFARIN (COUMADIN) are asked to monitor their PT/INR LEVEL regularly.PATIENT SELF TESTING makes it convenient for patients as they can easily perform their blood test by themselves with the help of PT/INR METERS at home and can get the reading in seconds.

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